What you actually say, in terms of the words you use, is something that you have to decide. You need to create an answer that sounds natural and, at the same time, interesting. 背答案估计没有人愿意听。The way to determine whether your answer is natural is simply by writing a first draft of the answer and then read it out loud. When you do this, you'll probably spot things that you have to change.
Here are some final things to think about when answering the question "Tell me about yourself."
Mention major awards or accomplishments that relate to your career;
Promote your strengths, but do not mention any of your weaknesses;
Try to be funny if you can, but don't force it;
Summarize your career and education, but don't recite a list;
Don't start with your date of birth;
Avoid information that is not career-related. The fact that you own a dog won't get you a job
Always answer this question
Try to sound natural
Relax and enjoy yourself!